HOW DOES TADALAFIL WORK?
Tadalafil is a member of a family of drugs called PDE5 Inhibitors.
Scientists discovered that cyclic guanosine monophosphate (cGMP) was
the
key to sustaining an erection.
They discovered that when a man gets sexually stimulated, a chain
reaction occurs in the tissue of the penis that results in elevated
levels of a substance called cyclic guanosine monophosphate (cGMP).
As long as there are sufficient levels of cGMP, the penis can remain
erect. The more cGMP, the more robust and durable the erection.
If you inhibit the degradation of cGMP it stays around in the penis
longer, producing a more durable erection.
Another way you can think of Tadalafils (and all other similar
medicines) is that it preserves the elevated levels of cGMP that are
created when a man is sexually stimulated for a stronger, more lasting
erection.
That's how Tadalafil works - Tadalafil blocks the enzyme
phosphodiesterase-5 (PDE5) which is responsible for the neutralization
of cGMP. Cialis (tadalafil) is a highly selective inhibitor of PDE5.
(PDE5 is not the only phosphodiesterase involved in the erectile
physiology but it appears to be the most important one).
The nice thing about PDE5 blockers is that they shouldn't cause
erections at inappropriate times because they only block degradation of
cGMP produced in reaction to sexual stimulation, such as thinking about
something sexy. If you are not being sexually stimulated, there is no
cGMP to protect, so the drug remains in the background.
HOW MUCH DO I TAKE?
Take only what your doctor recommends. The usual dose is 10mg (half a pill) 20 min before sex, Usually 1 dose is sufficient for 2 or 3 days. Do not take Tadalafil if on other medication that contains nitrates. Softtabs are disolved in the mouth, and will start working faster than the tablet version.
HOW LONG IS DELIVERY?
We dispatch our drugs from several offshore distribution centres, to
bring you your drugs as fast as possible, delivery time is 5-20 days
for
registered mail, or 3-7 days for DHL or FEDEX (Courier is only
available
on orders of $200 or more and costs $40). All orders are sent in a
plain
envelope and is totally discreet.
WHAT OTHER DRUGS DO YOU SELL?
We sell a wide selection of non controlled meds, that are available at a fraction of the price of brand name equivilents at our Popular online Pharmacy Best generic pharmacy .com.
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